Maytenus erythroxylonReissek (Celastraceae) ethanol extract presents antidiarrheal activityviaantimotility and antisecretory mechanisms

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Maytenus erythroxylon Reissek (Celastraceae) ethanol extract presents antidiarrheal activity via antimotility and antisecretory mechanisms

AIM To investigate the acute toxicity, phytochemical profile, antidiarrheal activity and mechanisms of action of Maytenus erythroxylon (M. erythroxylon) ethanol extract. METHODS A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity. Intestinal transit and gastric emptying protocols were used to evaluate a possible antimotility effect. KATP channels, nitric oxide, pre...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2017

ISSN: 1007-9327

DOI: 10.3748/wjg.v23.i24.4381